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What is sequence projection?

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You can select a specific position or add a visualisation of either protein specific data or data derived from the complete protein family.

Functionality

Available functionality for sequence projection (more features are under development):

  • AA-distributions for each residue
  • Protein mutation data (protein data)
  • Protein contact data (protein data) (only available for a structure)
  • Conservation data (family data)
  • Correlated mutation data (family data) to highlight positions that show co-evolution behaviour across the alignment
  • Family mutation data (family data) to highlight positions for which mutations are identified in literature across the alignment
  • Family contact data (family data) to highlight positions involved in different types of contacts derived from all structures of the alignment
  • Keyword mutation data (family data) to highlight positions for which mutations related to a specific keyword¬†were identified
  • Highlight Hotspot basket positions in your protein (family data)
  • Patent mutation data (family data) to highlight positions for which mutations have been mentioned in patent claims
  • Thermostability prediction data (prediction data)
  • Pathogenicity prediction¬†data (prediction data)