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System search summary Important things to look for when choosing the right system for your project:
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Here, you can simply copy your sequence and click the SEARCH button.
We have to go through a lot of data to find the right systems, thus the search might take up to 2 minutes.
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Sequence can be either a plain amino acid sequence (one-letter code) or a FASTA sequence. |
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Let’s say you’re interested in the catalytic domain (orange), then you can for example exclude the 2nd system in the list since it only covers the C-terminal hemopexindomains (red). In terms of coverage the last system seems like the best choice because it covers the full target sequence (but it’s not always the case - sometimes there are only systems that cover parts of the sequence).
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Next thing to check is how much data is there in these systems. This you can estimate from the two values Sequences and Mutations. So in this case, if you’re interested in the catalytic domain then the first system will be your best choice - it has the highest number of both sequences (7297) and mutations (5653). However, if you want to investigate the interactions of the catalytic domainwith the hemopexindomains then you should pick the last system that covers both parts - although it is significantly smaller (only 1580 sequences).
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